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Angina, or chest pain, has improved with L-carnitine supplements, exercise ability, and chest pain in those with cardiac syndrome X
Importantly, ferroptosis has been proven to be a common intervention target for halting DKD progression (187)
"ASPN guideline for painful diabetic neuropathy." J Pain Res 2024
This epigenetic regulation upregulates NLRP3 inflammasome activity, which subsequently triggers tubular cell pyroptosis, thereby exacerbating tubular damage and the progression of DKD (166)
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