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This event activates the subsequent apoptotic signaling pathways, ultimately causing cell apoptosis ( Furthermore, following IAA treatment, the levels of p-AKT, p-mTOR, p-p70, and p-GSK3 were found to be decreased (Yao et al., 2016)

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Lifestyle factors: 7-9 hours of quality sleep nightly Facial massage to improve circulation Stress management through meditation or exercise Avoid smoking and excessive sun exposure Exercise supports facial muscle tone and circulation