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Abstract Background The development of purple urine after methylene blue (methylthioninium chloride) and hydroxocobalamin co-administration is a rare clinical entity that has not been fully elucidated

Although our screening assay allows us to identify Bdnf inducers in neurons, it is difficult to clarify how active agents increase Bdnf transcription

Often, inadequate intake of glutathione and the nutrients needed for its production leads to glutathione deficiency

This property has made the peptide of particular interest in experimental models examining peptide signaling persistence and tissue-level regulatory pathways