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thereby, making the cell more resistant to intrinsic or extraneous stressors

Despite the promising findings reported in preclinical studies, it is important to emphasize that the majority of the available evidence originates from animal models and cell culture experiments

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cART generally consists of a combination of at least three antiretroviral drugs from distinct classes, typically two nucleoside reverse transcriptase inhibitors (NRTIs) combined with a third drug from one of three classes: HIV integrase strand transfer inhibitors (INSTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), or HIV protease inhibitors (PIs) with a pharmacokinetic enhancer 172