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In contrast, the promoters of lytic viral genes were found to display methylations associated to heterochromatin (Cliffe et al., Noteworthy, HSV-1 latency has been observed to be concentrated at specific sites in the CNS in studies consisting of a mouse model of herpes simplex encephalitis (HSE)
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Interestingly, animal models of WVS show abnormal neurogenesis in the cerebral cortex, cerebellum, and spinal cord during nervous system development
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