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Key MechanismsRedox Balance, Detoxification, & Neuroprotection Glutathione (GSH) governs cellular redox homeostasis and detoxifies reactive oxygen and nitrogen species (RONS), protecting neurons that are particularly vulnerable due to high metabolic demand and oxygen use

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In addition, G6PD-associated genes were highly correlated with autoimmune diseases, including amyotrophic lateral sclerosis, graft-versus-host diseases, and autoimmune thyroid disease