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Alpharael, Dreaming Acolyte is an expensive one-time looter and often trades with a 3/1, can do much better for three mana

However, the most powerful in all the Vileplume cards have to be the one belonging to Ancient Origins expansion, which with its 130 HP Stage 2 portfolio, has an ability called Irritating Pollen, blocking players from using any item cards

I was hoping to find at least 100 examples of openings to get a good sample size but through all of my research I only managed to find 63 (not including gold strips)

You just have to sit there as you lose the game while not being able to interact with the attacking creature(s) in any way